The path of primordial germ cells illustrates the complexities of imprinted DNA, which contains epigenetic marks that turn on and off when necessary. Differences between the maternal and paternal ...

Two weeks after a human egg is fertilized, primordial germ cells (PGCs), which develop into sperm and eggs, are formed. In six to 10 weeks after fertilization, PGCs differentiate into pro ...

This work is an important contribution to understanding the role of FGF signaling in the induction of primitive-like cells in a 2D system of human gastrulation. The authors provide compelling evidence ...