Nature3mon
Not so Fas: Re-evaluating the mechanisms of immune privilege and tumor escape
Based on early studies, it was hypothesized that expression of Fas ligand (FasL) by tumor cells enabled them to counterattack the immune system, and that transplant rejection could be prevented by ...
Nature9y
Fas counter-attack–the best form of tumor defense?
New in vivo evidence confirms that tumor-expressed Fas ligand ... immune effector cells. A recent report demonstrated that murine AK-5 tumor cells transiently upregulated FasL when grown in ...
News Medical on MSN9d
FasL inhibitor speeds recovery and reduces mortality in severe COVID-19 patients
A new clinical study shows that an inhibitor of Fas ligand (FasL), also called CD95 ligand (CD95L), led to a faster recovery ...