Nature3 个月
Not so Fas: Re-evaluating the mechanisms of immune privilege and tumor escape
Based on early studies, it was hypothesized that expression of Fas ligand (FasL) by tumor cells enabled them to counterattack the immune system, and that transplant rejection could be prevented by ...
Nature9 年
Fas counter-attack–the best form of tumor defense?
New in vivo evidence confirms that tumor-expressed Fas ligand ... immune effector cells. A recent report demonstrated that murine AK-5 tumor cells transiently upregulated FasL when grown in ...