Researchers at the University of Chicago have successfully captured detailed images of adhesion G protein-coupled receptors, ...

New research from the University of Chicago combines two powerful imaging techniques to study the complete structure of a ...

The extracellular region of an aGPCR extends from the cell membrane into space outside the cell, where it can bind to molecules and receptors from other cells. It consists of several domains ...

The common understanding of how to activate an aGPCR is that a ligand from outside the cell attaches to one of the extracellular domains and exerts force that separates the GAIN domain from its ...

Glycans can be incredibly complex and branched in structure, contributing to the stability of the extracellular domain of ...

Researchers reveal the structural details of apoB100's interaction with LDL receptors, offering insights into LDL ...