These medications inhibit the enzyme monoamine oxidase B (MAO-B), which breaks down dopamine in the brain. As a result, these medications help dopamine stay intact for your brain to use.

Research shows that reward-based learning requires the two neuromodulators to balance one another’s influence — like the accelerator and brakes on a car ...

We describe effects on dopamine, norepinephrine, MAO-A, and MAO-B activity, and on physiological and subjective effects of cocaine before and after one week of transdermal selegiline. Infusion ...