We describe effects on dopamine, norepinephrine, MAO-A, and MAO-B activity, and on physiological and subjective effects of cocaine before and after one week of transdermal selegiline. Infusion ...
These medications inhibit the enzyme monoamine oxidase B (MAO-B), which breaks down dopamine in the brain. As a result, these medications help dopamine stay intact for your brain to use.
a MAO-B = monoamine oxidase type B, MAO-A = monoamine oxidase type A. b Expressed as the molar concentration of drug required to inhibit enzyme activity by 50% (nmol/L). c Expressed as the ...