Divalproex sodium 250mg, 500mg; ext-rel tabs. Increased risk of hepatotoxicity in patients with congenital metabolic disorders, multiple AEDs, severe seizure disorders with mental retardation ...

Since divalproex ER dosage strengths (250 and 500mg) are not 12% higher than divalproex dosage strengths (125, 250 and 500mg), an 8-20% higher divalproex ER daily dose should be considered for ...