Dexamethasone phosphate (as sodium); 4mg/mL, 10mg/mL; soln for IV or IM inj; contains sulfites. Potentiated by CYP3A4 inhibitors (eg, ketoconazole, macrolides), cyclosporine, estrogens ...
Multi-day chemo: 6mos–<12yrs: 3mg/kg (max 115mg) IV once over 60mins on Day 1; then 2mg/kg (max 80mg ... Severe hepatic impairment. Injection: monitor for infusion site or hypersensitivity ...
A chart-review study found low-dose dexamethasone mixed with local anesthetic was the optimal injectate for use in ILESIs for lumbar radiculopathy.
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