How is all of that DNA packaged so tightly into chromosomes and squeezed into a tiny nucleus? Histones are a family of small, positively charged proteins termed H1, H2A, H2B, H3, and H4 (Van Holde ...

The study highlights how EV-DNA packaging influences immune responses and its promise as a biomarker for assessing colorectal ...

Both DNA binding sites in the globular domain are ... to the end of the chromatosome fragments when the endogenous linker histones are stripped. This seems to be the case for the bulk of the ...

Specially packaged DNA secreted by tumor cells can trigger an immune response that inhibits the metastatic spread of the tumor to the liver, according to a new study. The discovery improves the ...

Histones proteins were selected early in evolution to transform DNA into chromatin filaments formed by many nucleosomes. The ...

Specially packaged DNA secreted by tumor cells can trigger an immune response that inhibits the metastatic spread of the tumor to the liver, according to a study led by researchers at Weill Cornell ...

Genes make up the blueprints and outline the process of building every living organism. To ensure that the right genes are ...

The mechanism of a peculiar type of heterochromatin, used by embryonic stem cells to silence 'parasitic' DNA-elements within the context of their highly dynamic pluripotent chromatin. Disclaimer ...

We've now zoomed in enough to see portions of the DNA strand. The DNA is wrapped around histones -- protein structures that are sometimes depicted as discs. Histones carry a slight positive charge ...

Exposure to PM2.5 pollution poses significant risks to pregnant women by increasing inflammation levels, potentially leading ...

Exposure to PM2.5 pollution could lead to higher inflammation levels among pregnant women potentially resulting in adverse ...

His special expertise is on a very important group of proteins called histones that are used to package DNA in all organisms ...