Next-generation DNA sequencing has started a revolution ... this is very similar to the way in which gel or capillary sequencing is done,” notes Block. The results of initial experiments were ...
a method that separates DNA fragments by their sizes. The bands of the gel are detected, and then the sequence is read from the bottom of the gel to the top, including bands in all four lanes.
and Nanopore DNA sequencing. Sanger sequencing (left) sequences 500-700 bases per reaction with 16 reactions per gel. Massively parallel DNA sequencing (center) sequences 100-5,000 bases per reaction ...