Similarly to mice that lack other regulators of the cytoskeleton, HEM1-deficient T cells showed decreased activation and proliferation compared with wild-type T cells. Surprisingly, some T-cell ...

Juliano, R. L. Signal transduction by cell adhesion receptors and the cytoskeleton: Functions of integrins, cadherins, selectins, and immunoglobulin-superfamily members. Annual Review of ...

We aim to understand the molecular logic behind the dynamics of the actin cytoskeleton at endocytic sites and how disturbances in this process affect physiology and disease progression. Leonardo is ...

Single molecule imaging of H-Ras activation in living cells: The activation of H-Ras, a GTP-binding protein involved in the signaling pathways for cell proliferation and reorganization of the ...

"That signaling change leads to a switch in how ... CHRFAM7A diversifies human immune adaption through Ca2+ signalling and ...