The marks influence which genes are expressed or what levels they’re expressed at. Most methylation occurs at specific locations in the DNA, typically on a cytosine (C) that sits next to a guanine (G) ...

Not all genes are active at all times. DNA methylation is one of several epigenetic mechanisms that cells use to control gene expression. This straightforward experiment demonstrated that it was ...

Researchers can build models to predict gene expression by detecting and differentiating between cytosine methylation and hydroxymethylation marks in the genome. DNA methylation is an epigenetic ...

These medications work by acting like the nucleotide cytosine and incorporating ... the drugs block DNMT enzymes from acting, which inhibits DNA methylation. Drugs aimed at histone modifications ...

Each of these bricks is made up of 24 nucleotides (including cytosine sites for methylation) and encodes one bit of information, creating a stable and readable set through advanced sequencing ...

Study: CpGPT: a Foundation Model for DNA Methylation. Image Credit: Shutterstock AI In a recent pre-print* study posted to the bioRxiv server, a team of researchers introduced the Cytosine ...