In animal cells, DNA can be modified by methylation of cytosine residues in CpG dinucleotides, and the N-terminal tails of histone proteins are subject to a wide range of different modifications ...

The marks influence which genes are expressed or what levels they’re expressed at. Most methylation occurs at specific locations in the DNA, typically on a cytosine (C) that sits next to a guanine (G) ...

Researchers can build models to predict gene expression by detecting and differentiating between cytosine methylation and hydroxymethylation marks in the genome. DNA methylation is an epigenetic ...

Each of these bricks is made up of 24 nucleotides (including cytosine sites for methylation) and encodes one bit of information, creating a stable and readable set through advanced sequencing ...

Study: CpGPT: a Foundation Model for DNA Methylation. Image Credit: Shutterstock AI In a recent pre-print* study posted to the bioRxiv server, a team of researchers introduced the Cytosine ...