Nuclear condensates play many important roles in chromatin functions, but how cells regulate their nucleation and growth within the complex nuclear environment is not well understood. Here, we report ...
Coil cords, as they are sometimes called, consist of straight sections followed by curly sections. To achieve their spring-like form, the curly sections of metal wire are wound around a mandrel.
Letteri's lab, led by her Ph.D. advisee Vincent Gray, has demonstrated an approach for overcoming the longevity problem by designing mirror images of natural peptides called coiled coils.