the team were able to produce three-dimensional images of the clathrin, caveoli and actin filaments interacting within the membrane — impossible by using other techniques. Usukura says cryo-EM ...

Cryo-electron microscopy (cryo-EM) now offers a radically different way to study the structure of large biomolecules without the need to fabricate crystals. Protein structure has been ...

The authors also imaged the locations of partially assembled and empty clathrin cages—lattice-like ... for the empty cages found in neurons." Cryo-electron tomography is an imaging technique ...