In these cases, Down syndrome is caused by a translocation of chromosomes 15 and 21 (Figure 3), in which the long arms of two acrocentric chromosomes are translocated to produce a single long ...

Roughly 2,500-year-old DNA has revealed the first ancient person on record with Turner syndrome ... doesn't have 46 chromosomes, three individuals showed signs of Klinefelter syndrome — a ...

Translocations generate novel chromosomes, but are often linked to disorders like infertility and cancer. How do these new chromosomes generate problems, and how are they detected? Translocations ...

Courtesy of Greenwood Genetic Center. Segregation of a Robertsonian translocation: During this process, the short arms of 2 chromosomes are lost. The long arms fuse together at the centromere.

The journey of detecting and diagnosing Down syndrome ... is called a balanced translocation. No genetic material is gained or lost in a balanced translocation, so these chromosomal changes ...