Epigenetics involves genetic control by factors ... cause abnormally high gene activation by altering the arrangement of chromatin. On the other hand, too much methylation can undo the work ...

More recently, epigenetics has been defined as the study of mitotically and/or meiotically heritable changes in DNA. Cellular DNA is not “naked”, but is compacted into chromatin by histones.

Although epigenetic phenomena have been observed for over a century, researchers have only started to untangle their underlying mechanism and effects on gene expression. This course provides and ...

The Dang Lab is focused on the study of how epigenetics and chromatin regulate the process of aging. Our laboratory is studying epigenetic regulation mechanisms during aging and oncogenesis. Aging is ...

Our lab studies the epigenetics of complex traits: how genomes are packaged into chromatin, how chromatin landscapes are passed from one generation to the next, and how this transgenerational ...

Advances in epigenetic research have also opened up new opportunities in biotechnology and precision medicine. Epigenetic profiling techniques, such as DNA methylation sequencing and chromatin ...

This interesting study presents valuable information on how human cytomegalovirus (HCMV) infection disrupts the activity of the TEAD1 transcription factor, leading to widespread chromatin alterations.

Professor Kristian Helin’s group studies the role of chromatin-associated proteins (epigenetics) in the regulation of transcription, cell fate decisions and in cancer. The group is also using ...

Indeed, the neurons that were in a more open chromatin state were also the ones demonstrating higher electrical activity. The EPFL scientists then used a virus to deliver epigenetic enzymes to ...