Epigenetics involves genetic control by factors ... cause abnormally high gene activation by altering the arrangement of chromatin. On the other hand, too much methylation can undo the work ...

Although epigenetic phenomena have been observed for over a century, researchers have only started to untangle their underlying mechanism and effects on gene expression. This course provides and ...

While epigenetic studies have predominantly focused on chromatin and the use of specific enzyme inhibitors in vitro to prove their intracellular biologic role, more recent investigations have ...

This allows us to study chromatin biology with proteoform level specificity and observe quantitative changes to reveal mechanisms of disease. Our laboratory works at the intersection of three fields: ...

Epigenetic profiling techniques, such as DNA methylation sequencing and chromatin immunoprecipitation (ChIP), allow for the genome-wide mapping of epigenetic marks, providing valuable insights into ...

Indeed, the neurons that were in a more open chromatin state were also the ones demonstrating higher electrical activity. The EPFL scientists then used a virus to deliver epigenetic enzymes to ...

Professor Kristian Helin’s group studies the role of chromatin-associated proteins (epigenetics) in the regulation of transcription, cell fate decisions and in cancer. The group is also using ...

The Dang Lab is focused on the study of how epigenetics and chromatin regulate the process of aging. Our laboratory is studying epigenetic regulation mechanisms during aging and oncogenesis. Aging is ...