While epigenetic studies have predominantly focused on chromatin and the use of specific enzyme inhibitors in vitro to prove their intracellular biologic role, more recent investigations have ...

Although epigenetic phenomena have been observed for over a century, researchers have only started to untangle their underlying mechanism and effects on gene expression. This course provides and ...

This allows us to study chromatin biology with proteoform level specificity and observe quantitative changes to reveal mechanisms of disease. Our laboratory works at the intersection of three fields: ...

Advances in epigenetic research have also opened up new opportunities in biotechnology and precision medicine. Epigenetic profiling techniques, such as DNA methylation sequencing and chromatin ...

The Dang Lab is focused on the study of how epigenetics and chromatin regulate the process of aging. Our laboratory is studying epigenetic regulation mechanisms during aging and oncogenesis. Aging is ...

Our lab studies the epigenetics of complex traits: how genomes are packaged into chromatin, how chromatin landscapes are passed from one generation to the next, and how this transgenerational ...

Professor Kristian Helin’s group studies the role of chromatin-associated proteins (epigenetics) in the regulation of transcription, cell fate decisions and in cancer. The group is also using ...

The Whitehouse lab is broadly interested in understanding how chromatin functions in the regulation of cellular processes such as DNA replication, gene transcription and epigenetics. We focus on ...

Indeed, the neurons that were in a more open chromatin state were also the ones demonstrating higher electrical activity. The EPFL scientists then used a virus to deliver epigenetic enzymes to ...

"The role of insulators and transcription in 3D chromatin organisation of flies", Genome Research, 32:682-98 (PMID: 35354608) Grant OA, Wang Y, Kumari M, Zabet NR, Schalkwyk LC (2022) "Characterising ...