Each time they need to copy both their DNA and the structure in which the DNA is packed. This packaging, called chromatin, ...

In a recent paper published in the journal Genome Research, experts described the chromatin arrangement in the genomes of two ...

A study described the three-dimensional architecture of turtle genomes, which fold in a configuration unlike any other animal observed so far.

Cell-free DNA can be used for non-invasive cancer detection and disease monitoring to enhance personalized medicine.

New research finds that turtle genomes show a chromatin arrangement that hasn't been observed in other organisms.

In eukaryotes, DNA is tightly wound into a complex called chromatin. Thanks to the process of chromatin remodeling, this complex can be "opened" so that specific genes are expressed. Various ...

Chromatin as a guide Every day, our cells divide. Each time they need to copy both their DNA and the structure in which the DNA is packed. This packaging, called chromatin, acts as a guide. It tells ...

When genes are coiled and compacted into chromatin, they're no longer accessible to transcription factors. So how does the cell know where to uncoil in a process called chromatin remodeling?

cfDNA coverage shows an inverse relationship with both chromatin accessibility and gene expression levels, Using this relationship and machine learning identify patients with cancer.

In eukaryotes, genomic DNA is stored in the nucleus as nucleosomes, interacting with a set of proteins, forming a molecular complex called chromatin. The proper folding of the chromatin structure ...

Although epigenetic phenomena have been observed for over a century, researchers have only started to untangle their underlying mechanism and effects on gene expression. This course provides and ...