Drugs acting on the cholinergic system can improve or worsen cognitive abilities, and their effects are particularly pronounced in frail elderly individuals and patients with Alzheimer disease.

Neurones of one system, described and illustrated by us in the rat brain 1,2, contain acetylcholinesterase (AChE) throughout their length and are believed to be cholinergic, releasing ...

Although bronchial hyperresponsiveness to cholinergic agents is a main feature of asthma, the role of anticholinergic drugs in chronic asthma management has been largely underestimated. Several ...