Neflamapimod treatment previously led to significant reduction in plasma GFAP levels (p=0.015 versus placebo) and these reductions were associated with an improvement in clinical outcomes The ...

Additionally, we assume no period effects will be observed in the crossover ... Specifically, we will test the hypotheses that augmenting cholinergic neurotransmission will improve sway and ...

Drugs acting on the cholinergic system can improve or worsen cognitive abilities, and their effects are particularly pronounced in frail elderly individuals and patients with Alzheimer disease.

Cholinergic drugs (acetylcholine and methacholine ... showing an additional bronchodilator effect on top of the current asthma treatment. The first large study on unselected moderate asthmatics ...