For the first time, researchers have discovered that the accumulation of aged and failing cells, called senescent cells, in ...

In this study, our results uncover the function and mechanism of CHMP5 in the regulation of cell senescence and bone formation in osteogenic cells. Deletion of Chmp5 causes endolysosomal dysfunction ...

Professor Rajiv Jalan, study author from UCL Division of Medicine As the body gets older, cells become tired and stop working ...

The aging and failure of cells that occurs when one part of the body is damaged can spread to other organs, a study suggests.

The aging and failure of cells that occurs when the liver is damaged can spread to other organs, suggests a new study in mice ...

By examining nine mouse tissues, researchers pinpointed specific regions — known as senescence-sensitive spots (SSSs) — characterized by cellular disarray and a buildup of immunoglobulins. This ...

As the body gets older, cells become tired and stop working effectively. This process – called cell senescence – is a common effect of ageing but can also be triggered by diseases at any stage of life ...

When a telomere attains a critical short length, cells recognize it, and replication is attenuated, which results in cell senescence. Previous studies have indicated that magnesium maintains telomeric ...