This research investigates the molecular mechanisms by which SMAD2/3-SMYD2 and developmental transcription factors cooperate ...
Cells that progress through the cell cycle unchecked may eventually form ... and a reduction in the contact inhibition that normally prevents the cells from becoming too crowded.
LBS-007, a novel targeted therapy, has received FDA fast track designation for the treatment of acute myeloid leukemia.
Fast Track designation indicates LBS-007’s potential in filling the unmet medical need of acute leukemiaLBS-007 is the Company’s investigational ...
These compounds are specifically designed to inhibit the Topoisomerase II enzyme, a critical player in DNA replication and ...
Lin BioScience’s LBS-007 gets US FDA Fast Track Designation to treat acute myeloid leukaemia and acute lymphocytic leukaemia: Taipei City, Taiwan Friday, November 29, 2024, 12:0 ...
Cell-cycle inhibition can be achieved by pharmacological agents, irradiation or gene therapy ( Table 1). These can inhibit vascular proliferation by cytotoxic or cytostatic mechanisms. The ...
Title: CID-078, a First-in-Class Oral Macrocycle Cyclin A/B RxL Inhibitor ... tumor activity across tumor cell line and in vivo models with dysregulated cell cycle (CDK-RB-E2F) function.
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback