With prolonged use, concerns exist for the emergence of acquired fungal resistance and of Candida subspecies that are natively fluconazole-resistant (NFR), mostly Candida glabrata and Candida krusei.

which allow for rapid Candida albicans identification through the blue staining of the colonies after 48 hours incubation at 37°C. As a policy of our hospital, each fungal isolate is speciated.