Studies over more than a decade have generated a picture of how the external Env subunit (gp120) interacts first with the primary receptor (CD4) and then with a co-receptor (a chemokine receptor ...

Before fusion of the HIV viral envelope and host cell membrane can occur, an HIV glycoprotein complex consisting of glycoproteins gp41 and gp120 must bind with the CD4 receptor on the membrane of ...

HIV and treatments. On left, the HIV virus binds to CD4 T cell CD4 receptor, which will allow the ... [+] co-receptor CCR5 to melt and release the viral RNA into the cytoplasm. After reverse ...