As an orally available inhibitor of endothelin-1, which has been implicated in the pathogenesis of vascular disease in systemic sclerosis (SSc), bosentan is widely used as first-line therapy for ...

Bosentan is a dual endothelin-1-receptor antagonist that effectively treats idiopathic PAH and PAH related to connective tissue disease. Following preliminary trials of bosentan for the treatment ...

This leaflet answers some common questions about BOSENTAN VIATRIS. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist.

Bosentan 32mg; dispersible tabs for oral susp; tutti frutti flavor; contains phenylalanine. Must register patient in the Tracleer REMS Program (see full labeling). Take in the AM and PM.