Although it is clear that beta cell dysfunction is the main factor responsible for the progression to hyperglycemia, insulin resistance predates beta cell dysfunction, and reversibility of insulin ...
Chronic exposure to hyperglycemia can lead to cellular dysfunction that may become irreversible ... toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in ...
Among those who have had gestational diabetes, about 35% will develop type 2 diabetes within a decade. A new study reported in Science Advances is the first to identify molecular mechanisms of ...
About Menin’s Role in Diabetes Loss of functional beta cell mass is a core component of the natural history in both types of diabetes — type 1 diabetes (mediated by autoimmune dysfunction ...