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Beta blockers have been shown to prolong survival ... a β 1-selective "second-generation" β blocker, and carvedilol, a nonselective and vasodilatative "third-generation" β blocker.

Initiation or switching β blockers is not recommended in patients ... and an overlapping strategy in which a first- or second-generation β blocker is weaned while carvedilol is simultaneously ...

The Department of Health and Social Care have banned the use of puberty blockers in the UK for those under 18 indefinitely.