Thirty years after the sequencing of the BRCA1 cancer-associated gene, access to genetic tests and awareness about its risks ...

Patients with germline BRCA mutations who were diagnosed with breast cancer at or before age 40 and who underwent a bilateral ...

新研究表明在HER2阳性乳腺癌患者中，胚系BRCA1/2突变的发生率为6.6%，且不影响生存结果。乳腺癌是女性最常见的恶性肿瘤，遗传易感性作为其主要风险因素，在全部乳腺癌病例中占比达5%-10%。其中，约50%的病例与乳腺癌相关基因BRCA1和BRC ...

Patients with germline BRCA mutations who were diagnosed with breast cancer at or before age 40 and who underwent a bilateral risk-reducing mastectomy (RRM) and/or a risk-reducing ...

外婆、妈妈、女儿，祖孙三代被癌症基因困扰。正打算怀孕生子的女儿不想将这癌症基因再遗传给下一代，如何才能打破这一“魔咒”？祖孙三代先后患病源头竟指向同一致癌基因2021年，当时23岁的莺歌婚后打算备孕，可是过了一年多，肚子一直没动静。去年6月，她和丈夫 ...

A breakthrough study has identified the genetic risk factors that contribute to increased prostate cancer in African men. The ...

中国科学院院士黄荷凤团队接下了这个“拆弹”的重任，尝试在辅助生殖过程中，对复杂疾病通过多基因遗传风险评分方法，对胚胎进行多基因疾病遗传风险评估，筛选疾病风险最低的胚胎移植，从而实现多基因遗传病的一级防控。

Accent Therapeutics, a clinical-stage biopharmaceutical company pioneering novel, targeted, small molecule cancer ...

Patients with germline BRCA mutations who were diagnosed with breast cancer at or before age 40 and who underwent a bilateral ...

“但是肿瘤比较特殊，它属于多基因遗传病。”黄荷凤院士说，肿瘤的发生具有家族聚集性和遗传易感性，某些基因突变会增加患癌症的风险。比如携带BRCA1和BRCA2基因突变，会使女性70岁以前患乳腺癌的风险分别达到44%-78%和31%-56%。

It was more than 11 years ago that my patient Angelina Jolie – a carrier of the BRCA gene mutation – provided me with an ...