Our results show that degradation of chondroitin sulfate using chondroitinase ABC can render the environment of the damaged CNS more permissive to axon regeneration. This result confirms that ...

RhoA is a key protein in the intracellular signalling cascades that mediate growth cone collapse and contribute to the failure of axonal regeneration in the injured mammalian CNS. However ...

Capitalizing on potent intrinsic transcriptional programs for axon regeneration can provide opportunities for improving peripheral nerve repair and overcoming the permanent loss of function following ...

NervGen is engaged in groundbreaking research in spinal cord injury treatment. Read here for an update on the research's ...

Animal models as well as human cells have shown that cnicin significantly accelerates axon (nerve fibers) growth. The study ...

Multiple Sclerosis is a debilitating neurodegnerative disease of the central nervous system in which the immune system targets and destroys myelin sheaths surrounding axons. Progressive and permanent ...

increased CNS inflammation, death Trial planned on primary progressive MS (Yale University, New Haven, CT, USA); study placed on hold Flecainide Antiarrhythmic agent Protects axons, reduces ...

Myelin is an insulating structure that wraps around axons, allowing the ... and myelin regeneration fails. Oligodendrocyte progenitor cells (OPCs) are the major source of newly formed myelinating ...

The new Interactive Biomaterials for Neural Regeneration (InteReg ... lead to degeneration of the axons and permanent loss of central nervous system functions. Around three million individuals ...