Recent evidence suggests that multiple sclerosis also affects neurons, as cortical atrophy is detected early in the disease, axon transection can occur in inflammatory lesions, and axonal loss is ...

We now know that the axon has only a modest repertoire of ... Friedreich's ataxia), and even in the late sequelae of multiple sclerosis. Most of these degenerations share pathological features ...

Voltage-gated sodium channels can contribute to axonal injury in multiple sclerosis (MS ... and they prevent axon degeneration, maintain impulse conduction, and improve clinical status in ...

The University College London and Multiple Sclerosis Institute ... and they prevent axon degeneration, maintain impulse conduction, and improve clinical status in experimental autoimmune ...

Here's a quick primer on multiple sclerosis. MS is an autoimmune disease ... In severe cases, MS can attack the axon, the ...

and multiple sclerosis. The three best examples of ion channel/receptor clustering in the nervous system are found at the synapse, the node of Ranvier, and the axon initial segment (AIS). In the case ...

In multiple sclerosis the usually tightly regulated placement and concentration of VGSCs along the axon is profoundly altered following demyelination. It is believed that an increase in Na(v)1.6, a ...

and functionally restoring movement in the paralyzed legs of mice subjected to an autoimmune-mediated demyelinating model of human multiple sclerosis (MS). The research report titled ...