For example, the results of a study reported on page 291 of this issue of Nature ... so than aspirin. It is now known that all of these drugs block the activities of cyclooxygenase (COX), enzymes ...

Cyclo-oygenase (COX) was the key enzyme that these drugs ... Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature (New Biology) 231, 232–235 (1971).

a positive correlation with the potency of NSAIDs to inhibit COX and their potency to induce asthmatic attacks; and (3) cross-desensitization to other NSAIDs after desensitization to aspirin. Descript ...

Aspirin blocks the effects of the COX enzymes, proteins involved in inflammation and found at unusually high levels in several types of cancer. But regular use of the anti-inflammatory drug ...

Further studies are needed to replicate the results of previous studies on COX-2 genetic polymorphisms and aspirin ... Given the chronic nature of CAD, there is a need for cost-effective ...