Illustration of three-step DOTA-PRIT based on targeting with an IgG-scFv bispecific antibody (e.g., huA33-C825 for detection and treatment of colorectal cancer) with dual specificity for a ...

As shown on the right, TES release the interleukin IL-2, which stimulates CAR-T cells to multiply, and anti-CD3 and anti-CD28, two antibodies that, similar to tumor antigens presented by an ...