Objectives: To investigate whether analgesic and sedative drug use during PICU treatment is associated with long-term neurodevelopmental outcome in children who survived meningococcal septic shock.

Over a 15-year period, prescriptions for analgesics and sedatives to manage HICP decreased while prescriptions for gabapentinoids increased.

Sedation as a side effect of metoclopramide ... Whether metoclopramide has an intrinsic analgesic effect is still under debate 13,14. However, several studies have reported analgesic action ...