Amyloid precursor protein (APP) is a type I integral membrane protein ubiquitously expressed in many tissues and concentrated in the synapses of neurons. It has three predominant splice variants ...

We examined acetylcholinesterase, plasma neuronal proteins, secreted beta-amyloid precursor protein (APP), and amyloid-beta 40 and amyloid-beta 42 peptides in children with and without autism.

Amyloid beta (Aβ) peptide, a 40-42 amino acid protein cleaved from the amyloid precursor protein (APP), is a main constituent of the amyloid plaques found in the brains of Alzheimer Disease (AD ...

Adding lipids from higher organisms to the bacteria's growth medium also boosts yield of functional protein. Sanders says his approach has been successful for producing the amyloid beta precursor ...

As its name suggests, BACE cleaves amyloid-beta precursor protein (APP), which is involved in producing amyloid beta. "Oligodendrocytes lacking BACE1 developed about 30 percent fewer plaques ...

A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of ...

A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of ...

A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of ...

Combining these commonly found ingredients into a drink could protect against arthritis and strengthen the immune system ...

Valiltramiprosate is under clinical development by Alzheon and currently in Phase II for Unspecified Central Nervous System Disorders.