Following a 2-week placebo run-in, 440 adults (45-80 years old) were randomized to receive either amlodipine 5 mg once daily or losartan 50 mg once daily. Patients who failed to meet the sitting ...

Adult: PO Per tab contains amlodipine 5 mg and losartan potassium 50 mg: The recommended initial dose is 1 tab/day; it may be increased up to 2 tab/day.

Of the patients who required the higher dose (amlodipine 10 mg, N=120; losartan 50 mg/HCTZ 12.5 mg, N=136), the percentage of patients reaching sDBP goal was significantly greater in patients ...

Adult: PO Per tab contains amlodipine 5 mg and losartan potassium 50 mg: The recommended initial dose is 1 tab/day; it may be increased up to 2 tab/day. • Caution should be exercised in patients ...