pharmaphorum1y
Morphic loses second partner as J&J exits integrin alliance
Morphic had previously also entered into a research collaboration with AbbVie, focusing on alpha V beta 6 integrin inhibitors, but rights to that were returned to the biotech after a safety signal ...
Next-gen gene therapy vector for muscle diseases uses AI predictive methodology to improve efficacy and safety
The article, published in Nature Communications, is titled "An engineered AAV targeting integrin alpha V beta 6 presents improved myotropism across species." "The era of gene therapy for ...
Nature2y
A sharper diagnosis for ulcerative colitis
They discovered that patients with ulcerative colitis carry autoantibodies that target integrin alpha-v/beta-6, a protein that connects epithelial cells in the intestine to other types of tissue.
pharmaphorum1y
Takeda tries again with subcutaneous Entyvio
The new formulation of the alpha-4 beta-7 integrin antagonist is intended for use after the current intravenous formulation of Entyvio (vedolizumab) is deployed as an induction therapy for the ...