Diagnosis Tophaceous gout associated with urate nephropathy in a patient intolerant to allopurinol. Management Acute polyarthritis was successfully managed by intravenous bolus methylprednisolone ...

complicating gout management." "This practice, often reported anecdotally by rheumatologists who note that 'nephrologists keep lowering my patient's allopurinol for no reason,' contributes to ...

One regimen to consider for those commencing allopurinol at an early stage of gout presentation in a patient with normal renal function is to wait 3 weeks after an acute attack resolves ...

In addition, allopurinol is typically given with colchicine to reduce the short-term risk of a gout attack. Allopurinol side effects include stomach upset and rare, but often serious, skin reactions.

XORTX Therapeutics (XRTX) announces the launch of a new late stage program to treat gout. The new drug development program – XRx-026 – will ...

The new drug development program - XRx-026 - will focus on the treatment of individuals who have gout and are intolerant to allopurinol. With the clinical development of XORLO TM 1 having advanced ...

With the clinical development of XORLO TM1 having advanced sufficiently, including completion of a pivotal program, XORTX is initiating discussions for the XRx-026 program with the US Food and Drug ...

XORTX to focus on late stage allopurinol intolerant gout program; discussion with FDA planned for first half 2025 regarding NDA filing CALGARY, Alberta, Jan. 06, 2025 (GLOBE NEWSWIRE) -- XORTX ...

(MENAFN- GlobeNewsWire - Nasdaq) XORTX to focus on late stage allopurinol intolerant gout program; discussion with FDA planned for first half 2025 regarding NDA filing With the clinical ...