The allele frequency represents the incidence of a gene variant in a population. Alleles are variant forms of a gene that are located at the same position, or genetic locus, on a chromosome.

The Hardy-Weinberg theorem characterizes the distributions of genotype frequencies in populations that are not evolving, and is thus the fundamental null model for population genetics. Under the ...

The equilibrium for a population with the alleles A and a, for example, would be allele frequencies of .6A and .4a and genotype frequencies of .36AA, .48Aa, and .16aa. By describing specific ideal ...

"Currently, guidelines do not recommend testing for the TPMT∗8 variant, which is a variant common among individuals of African or African American ancestry (2.3% minor allele frequency ...