Both infiltrating immunoinflammatory cells and adipocytes play critical roles in the modulation of metabolic homeostasis, so it is important to understand factors that regulate both adipocyte and ...

Enlargement of adipocytes is the main mechanism of weight gain in adults, but total fat is also influenced by adipocyte numbers—obese people, on average, have more adipocytes than nonobese people.

Conversely, depletion of FAM3C in CAAs leads to adipocyte-mesenchymal transition (AMT) and increased fibrosis within the TME. The research team also discovered that breast cancer cells stimulate ...