We have been exploring the potential of the neuromodulator, adenosine, to reduce excessive dopamine signaling that contributes to the development and persistence of psychostimulant abuse. Dopamine’s ...

Image courtesy of Philip Rawlins et al., in partnership with ELRIG (UK) Ltd. The Domainex fragment library (960 fragments) was screened at 250 μM against adenosine A2A receptor using spectral shift.