Acyclovir gets converted to acyclovir triphosphate, which then inhibits replication of herpes viral DNA by competitively inhibiting viral DNA polymerase, incorporating into and terminating the ...
A: The first antiviral drug developed for herpes simplex infections was Zovirax (acyclovir). It was first approved in 1982 as a topical cream to treat cold sores. Oral tablets also became available; ...
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