try to win Thomas Brown's debut as interim head coach. The Series: The 70th game between the teams. The 49ers lead 35-33-1.

Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...

One of the main issues plaguing the San Francisco 49ers this year is execution. A lot of players have been playing poorly and ...

The 49ers shored up their suddenly thin running back corps on Tuesday by claiming Israel Abanikanda off waivers from the New ...

Sondra Williams, the wife of San Francisco 49ers tackle Trent Williams, said on social media that their son, Trenton, was ...

The 49ers opened the practice window for safety Talanoa Hufanga, who has missed the last seven games with a wrist injury.

While a sense of gratitude is well and nice we also have some thoughts on teams that are failing in epic ways and have to ...

Mia DeCamilla, an eight-year-old San Francisco 49ers fan and cancer survivor, was attending her first NFL game on Sunday ...

News of the Williams family’s stillborn comes a month after 49ers player Charvarius Ward’s 1-year-old daughter, Amani Joy, ...

After Trent Williams and wife Sondra shared the devastating loss of their son Trenton O'Brien Williams Jr. from a stillbirth, ...

NFL Week 14 odds, picks, predictions, TV channel, streaming information for Sunday football game between Chicago Bears and ...