PARP-1 Active Site - 搜索图片

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researchgate.net
Docking models of the PARP1 – HPF…
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science.org
Structural basis for allosteric PARP-1 retention on DNA breaks | Science
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mdpi.com
Cancers | Free Full-Text | Epigenetic Insights on PARP-1 Activity in Cance…
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cell-stress.com
Poly(ADP-ribose) polymerase-1 and its ambiguous role in cellular life and death

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researchgate.net
Binding mode of compound 8a in PARP-1 active site. | Download Scientific Diagram
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researchgate.net
Binding mode of compound 8f in PARP-1 active site. | Download Scientific Diagram
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researchgate.net
Binding mode of compound 8k in PARP-1 active site. | Downloa…
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researchgate.net
Binding mode of compound 8k in PARP-1 active site. | Downloa…

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pnas.org
Inhibitors of PARP: Number crunching and structure gazing | P…
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researchgate.net
A Mechanism of action of PARP inhibitors: (a) Single-strand brea…
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MDPI
IJMS | Free Full-Text | PARP1 in Carcinomas and PARP1 Inhibitors as Antineoplastic Drugs
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oncologypro.esmo.org
Mode of Action | OncologyPRO

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researchgate.net
2D interaction diagram showing Olaparib (lead …
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pubs.rsc.org
Discovery of pyrano[2,3- d ]pyrimidine-2,4-dione derivatives as novel PARP-1 inhibitors: design ...
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genesdev.cshlp.org
Poly(ADP-ribosyl)ation by PARP-1: `PAR-laying' NAD+ into a nuclear si…
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researchgate.net
Role of PARP1 in DNA repair: DNA damage activates PARP1 enzyme.…

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bocsci.com
Beyond PARP1 Single-Target Inhibitors–Combined Therapy Reveals Mor…
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pubs.rsc.org
Discovery of pyrano[2,3- d ]pyrimidine-2,4-dione derivatives as novel PARP-1 inhibitors: design ...
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frontiersin.org
Frontiers | Human PARP1 substrates and regulators of its catalytic activit…
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frontiersin.org
Frontiers | The Critical Role of PARPs in Reg…

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researchgate.net
PARP-1 activity is required for efficient Che-1 accumulation i…
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researchgate.net
Identification of PARP-1. Several approaches were used to identi…
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researchgate.net
Positions of 7mGua (a) and 8h7mGua (b) inhibitors in the PARP1 active...
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Royal Society of Chemistry
Design, synthesis and in silico studies of new quinazolinone derivatives as antitumor PARP-1 ...

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researchgate.net
PARP-1 catalytic activity promotes the phosphorylation of STAT1α on…
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researchgate.net
Figure S4. Top IFD scores of the similar ligands (>70% structural... | Download Scient…
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obroncology.com
Selective PARP1 Inhibitor Shows Activity, Safety in Early-Stage Trial
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researchgate.net
PARP-1 is acetylated upon stimulation in vivo …

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pubs.rsc.org
Discovery of pyrano[2,3- d ]pyrimidine-2,4-dione derivative…
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Frontiers
Frontiers | Poly(ADP-Ribose)Polymerase (PARP…
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researchgate.net
Positions of 7mGua (a) and 8h7mGua (b) inhibitors in t…
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researchgate.net
Inhibition of PARP-1 activity leads to decre…
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mdpi.com
Cancers | Free Full-Text | Epigenetic Insights on PARP-1 …

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researchgate.net
Functional states of PARP-1. Inactive forms have been drawn in black,... | Do…
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europepmc.org
PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Do…

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